Glycerol Teichoic Acid as a Common Antigenic Factor in Lactobacilli and Some Other Gram-positive Organisms
نویسندگان
چکیده
منابع مشابه
Synthetic Teichoic Acid Conjugate Vaccine against Nosocomial Gram-Positive Bacteria
Lipoteichoic acids (LTA) are amphiphilic polymers that are important constituents of the cell wall of many Gram-positive bacteria. The chemical structures of LTA vary among organisms, albeit in the majority of Gram-positive bacteria the LTAs feature a common poly-1,3-(glycerolphosphate) backbone. Previously, the specificity of opsonic antibodies for this backbone present in some Gram-positive b...
متن کاملInvestigating Gram-positive Wall Teichoic Acid Investigating the Dispensability of Wall Teichoic Acid in the Gram-positive Bacteria Bacillus Subtilis and Staphylococcus Aureus
In recent decades, the emergence of multi-drug resistant pathogenic organisms has proven to be a significant threat to human health. Today, resistant organisms have been identified for every class of antibiotics introduced into clinical practice. Combining this with the knowledge that the introduction of new antimicrobial classes has been almost non-existent since the early 1960's, stresses the...
متن کاملPurification and evaluation of glycerol teichoic acid from biofilm forming Staphylococcus epidermidis as a putative vaccine candidate
Introduction: Biofilm forming Staphylococcus epidermidis is a main causative agent of infections related to medical devices. Purification and evaluation of Gly-TA polysaccharide from a biofilm-forming S. epidermidis as a putative vaccine candidate were the main goals of the current study. Methods: Taking advantage of size exclusion chromatography procedure, glycerol teichoic acid (Gly-TA) was p...
متن کاملThe glycerol teichoic acid from walls of Staphylococcus epidermidis I2.
1. Walls of Staphylococcus epidermidis I2 contain 30% (w/w) of a glycerol teichoic acid containing phosphate, d-alanine and d-glucose in the molecular proportions 1:0.25:0.50. 2. The teichoic acid was isolated by extraction with trichloroacetic acid and with dilute aqueous NN-dimethylhydrazine at pH7, and was shown to be a (1-->3)-linked poly(glycerol phosphate) containing beta-d-glucopyranosyl...
متن کاملCEM-101 activity against Gram-positive organisms.
The in vitro activity of CEM-101, a new fluoroketolide, was determined against Gram-positive organisms with various macrolide susceptibility profiles. Experiments for determination of the MICs and minimum bactericidal concentrations (MBCs), timed killing, single-step and multistep mutation rates, the erythromycin induction of resistance, postantibiotic effect (PAE), and drug interactions were p...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of General Microbiology
سال: 1973
ISSN: 0022-1287
DOI: 10.1099/00221287-74-1-119